@article{Yang2012, 
author = {Tianshe Yang and Qian Liu and Shouzhi Pu and Zesheng Dong and Chunhui Huang and Fuyou Li},
title = {Fluorophore–Photochrome Co-Embedded Polymer Nanoparticles for Photoswitchable Fluorescence Bioimaging},
year = {2012},
journal = {Nano Research},
volume = {5},
number = {7},
pages = {494-503},
keywords = {Photoswithable imaging, polymer nanoparticles, fluorophore–photochrome, living cell},
url = {https://www.sciopen.com/article/10.1007/s12274-012-0235-0},
doi = {10.1007/s12274-012-0235-0},
abstract = {Photoswitchable polymer nanoparticles (ps-PNPs) have been constructed by emulsion polymerization through embedding an iridium(Ⅲ) complex, [Ir(bt)2(pic)] (bt = phenylbenzothiazole, pic = picolinate), as a fluorophore and a diarylethene derivative (DTE) as a photochrome. The ps-PNPs show reversible luminescence modulation with DTE switching using UV light in aqueous solution and even in living cells. Such luminescent modulation only occurred in polymer nanoparticles and not in a simple mixed solution with low concentrations of [Ir(bt)2(pic)] and DTE. The ps-PNPs displayed good cellular uptake and fast intracellular luminescence modulation by photoswitching, indicating the nanoparticles could be developed as photoswitchable luminescent probes for a diversity of bioimaging applications.}
}