@article{Liu2019, 
author = {Yang Liu and Xiaorui Tian and Weiran Guo and Wenqiang Wang and Zhiqiang Guan and Hongxing Xu},
title = {Real-time Raman detection by the cavity mode enhanced Raman scattering},
year = {2019},
journal = {Nano Research},
volume = {12},
number = {7},
pages = {1643-1649},
keywords = {surface enhanced Raman scattering, cavity modes, microfluidics, bi-analyte, real-time detection},
url = {https://www.sciopen.com/article/10.1007/s12274-019-2414-8},
doi = {10.1007/s12274-019-2414-8},
abstract = {Integrating surface enhanced Raman scattering (SERS) with microfluidics is the long-term goal for reduced volume, multiplex and automation fingerprint detection of biomolecules. High sensitivity, repeatability, stability, reusability and real-time detection are the performance goals of Raman detection in the aqueous solution environment. Here, we reported the study on cavity mode enhanced SERS detection of both surface-adsorbed molecules and non-surface-adsorbed molecules in the solution environment. The cavity modes had important influence on the SERS enhancement, especially for the non-surface adsorbed molecules. Uniform, repeatable, reusable and real-time Raman signal detection of the non-surface adsorbed Rhodamine 6G molecules was demonstrated. Our work is an important step for the practical on-chip microfluidic Raman detection applications.}
}