@article{Yan2019, 
author = {Junjie Yan and Xudong Zhang and Yang Liu and Yanqi Ye and Jicheng Yu and Qian Chen and Jinqiang Wang and Yuqi Zhang and Quanyin Hu and Yang Kang and Min Yang and Zhen Gu},
title = {Shape-controlled synthesis of liquid metal nanodroplets for photothermal therapy},
year = {2019},
journal = {Nano Research},
volume = {12},
number = {6},
pages = {1313-1320},
keywords = {nanomedicine, photothermal therapy, liquid metal, melanin nanoparticles, shape-controlled synthesis},
url = {https://www.sciopen.com/article/10.1007/s12274-018-2262-y},
doi = {10.1007/s12274-018-2262-y},
abstract = {The capping agents for liquid metal (LM) nanodroplets in aqueous solutions are restricted to thiol-containing and positively-charged molecules or macromolecules. However, both thiolate-metal complex and electrostatic interaction are liable to detachment upon strong mechanical forces such as sonication, leading to limited stability and applications. To address this, we utilized ultrasmall water soluble melanin nanoparticles (MNPs) as the capping agent, which exhibited strong metal binding capability with the oxide layer of gallium based LMs and resulted in enhanced stability. Interestingly, shape-controlled synthesis of LM nanodroplets can be achieved by the incorporation of MNPs. Various EGaIn nanostructures including nanorice, nanosphere and nanorod were obtained by simply tuning the feed ratio, sonication time, and suspension temperature. Among these shapes, EGaIn nanorice has the best photothermal conversion efficiency, which could be leveraged for photothermal therapy.}
}