@article{Zhou2018, 
author = {Weiqiang Zhou and Hongfeng Li and Bin Xia and Wenlan Ji and Shaobo Ji and Weina Zhang and Wei Huang and Fengwei Huo and Huaping Xu},
title = {Selenium-functionalized metal-organic frameworks as enzyme mimics},
year = {2018},
journal = {Nano Research},
volume = {11},
number = {10},
pages = {5761-5768},
keywords = {metal-organic frameworks, nano chemistry, selenium chemistry, enzyme mimic, postsynthetic modification},
url = {https://www.sciopen.com/article/10.1007/s12274-017-1623-2},
doi = {10.1007/s12274-017-1623-2},
abstract = {The development of artificial enzyme mimics has been rapidly growing in recent years, and it is attracting increasing attention owing to their remarkable advantages over natural enzymes. Herein, we developed a general and facile method to fabricate efficient glutathione peroxidase (GPx) mimics by grafting selenium-containing molecules (phenylselenylbromide, PhSeBr) to a Zr(IV)-based UiO-66-NH2 framework. In the presence of glutathione (GSH) serving as substrate, the fabricated UiO-66-Se catalysts can catalyze the reduction of hydroperoxides. The as-prepared UiO-66-Se systems show good catalytic activity over three cycles. These high-efficiency GPx mimic metal-organic frameworks (MOFs) are endowed with excellent thermal and structural stability, providing a promising avenue for the development of artificial enzyme mimics.}
}