Journal Home > Online First

Full text
About this article

Cerebellar circuits in autism-linked social behavior

Show Author's information Shaofei Jiang1,2Yingping Ma3Xiangjun Hu2Haitao Wu1,3,4,5( )
Department of Neurobiology, Beijing Institute of Basic Medical Sciences, Beijing 100850, China
Laboratory of Experimental Pathology, Beijing Institute of Radiation Medicine, Beijing 100850, China
School of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China
Key Laboratory of Neuroregeneration, Co-innovation Center of Neuroregeneration, Nantong University, Nantong 226019, China
Chinese Institute for Brain Research, Beijing 102206, China


Stoodley, C. J., Tsai, P. T. Adaptive prediction for social contexts: The cerebellar contribution to typical and atypical social behaviors. Annual Review of Neuroscience, 2021, 44: 475–493.
Stoodley, C. J., D'Mello, A. M., Ellegood, J., Jakkamsetti, V., Liu, P., Nebel, M. B., Gibson, J. M., Kelly, E., Meng, F. T., Cano, C. A. et al. Altered cerebellar connectivity in autism and cerebellar-mediated rescue of autism-related behaviors in mice. Nature Neuroscience, 2017, 20(12): 1744–1751.
Kelly, E., Meng, F. T., Fujita, H., Morgado, F., Kazemi, Y., Rice, L. C., Ren, C. Y., Escamilla, C. O., Gibson, J. M., Sajadi, S. et al. Regulation of autism-relevant behaviors by cerebellar-prefrontal cortical circuits. Nature Neuroscience, 2020, 23(9): 1102–1110.
Carta, I., Chen, C. H., Schott, A. L., Dorizan, S., Khodakhah, K. Cerebellar modulation of the reward circuitry and social behavior. Science, 2019, 363(6424): eaav0581.
Cutando, L., Puighermanal, E., Castell, L., Tarot, P., Belle, M., Bertaso, F., Arango-Lievano, M., Ango, F., Rubinstein, M., Quintana, A. et al. Cerebellar dopamine D2 receptors regulate social behaviors. Nature Neuroscience, 2022, 25(7): 900–911.
Publication history
Rights and permissions

Publication history

Received: 27 December 2022
Revised: 05 January 2023
Accepted: 10 January 2023
Published: 08 February 2023


© The Author(s) 2023


This work is supported by the National Natural Science Foundation of China (Nos. 32171148 and 31770929) and the National Key Research and Development Program of China (Nos. 2021ZD0202500 and 2021YFA1101801).

Rights and permissions

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attributtion-NonCommercial 4.0 License ( which permits non-commercial use, reproduction and distribution of the work without further permission.