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Case Report | Open Access

Diagnosis and treatment of micro-entrapment syndrome of nerves innervating the face: A report of two cases

The First Clinical Medical College of Beijing University of Traditional Chinese Medicine, Beijing 100700, China
Yuquan Hospital, Tsinghua University, Beijing 100049, China
Department of Neurosurgery, Dongzhimen Hospital, Beijing University of Traditional Chinese Medicine, Beijing 100700, China

§ These authors contributed equally to this work.

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The term "micro-entrapment syndrome of nerves innervating the face (MESNIF)" is a relatively new concept. It refers to the micro-entrapment of facial nerve (trigeminal nerve and facial nerve) terminals for various reasons, resulting in one-side facial discomfort, subjective sensory abnormalities, or stiffness, and in certain cases, localized micro muscle movement abnormalities and motor disharmony. It is frequently caused by facial paralysis or chronic trigeminal neuritis or injury, and is prevalent in clinical practice. Peripheral facial paralysis affects 60%-70% of people. Both men and women are susceptible to it. It is most common in young and middle-aged women. At the moment, there are two types of therapy options for this disease: nonsurgical treatments and surgical treatments. Among surgical treatments, pulsed radiofrequency has good curative results. This paper describes two typical situations that had good curative effects.


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Journal of Neurorestoratology
Pages 66-71
Cite this article:
Xu M, Lin N, Li J, et al. Diagnosis and treatment of micro-entrapment syndrome of nerves innervating the face: A report of two cases. Journal of Neurorestoratology, 2022, 10(1): 66-71.








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Received: 07 November 2021
Revised: 25 January 2022
Accepted: 05 March 2022
Published: 05 March 2022
© The authors 2022.

This article is published with open access at, distributed under the terms of Creative Commons Attribution 4.0 International License (CC BY).