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Journal of Neurorestoratology 2019, 7(3): 116-128 https://doi.org/10.26599/JNR.2019.9040017
Review Article | Open Access | Issue | Published: 09 October 2019

The Golgi apparatus in neurorestoration

Show Author's Information Jianyang Liu,  Jialin He,  Yan Huang,  Han Xiao,  Zheng Jiang,  Zhiping Hu( )
Department of Neurology, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan, China
Keywords:
neurodegeneration, Golgi apparatus, neurogenesis, synaptogenesis, angiogenesis
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Liu J, He J, Huang Y, et al. The Golgi apparatus in neurorestoration. Journal of Neurorestoratology, 2019, 7(3): 116-128. https://doi.org/10.26599/JNR.2019.9040017
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Abstract Full text About this article

The central role of the Golgi apparatus in critical cellular processes such as the transport, processing, and sorting of proteins and lipids has placed it at the forefront of cell science. Golgi apparatus dysfunction caused by primary defects within the Golgi or pharmacological and oxidative stress has been implicated in a wide range of neurodegenerative diseases. In addition to participating in disease progression, the Golgi apparatus plays pivotal roles in angiogenesis, neurogenesis, and synaptogenesis, thereby promoting neurological recovery. In this review, we focus on the functions of the Golgi apparatus and its mediated events during neurorestoration.


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About this article

The Golgi apparatus in neurorestoration

Show Author's information Jianyang Liu, Jialin He, Yan Huang, Han Xiao, Zheng Jiang, Zhiping Hu( )
Department of Neurology, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan, China

Abstract

The central role of the Golgi apparatus in critical cellular processes such as the transport, processing, and sorting of proteins and lipids has placed it at the forefront of cell science. Golgi apparatus dysfunction caused by primary defects within the Golgi or pharmacological and oxidative stress has been implicated in a wide range of neurodegenerative diseases. In addition to participating in disease progression, the Golgi apparatus plays pivotal roles in angiogenesis, neurogenesis, and synaptogenesis, thereby promoting neurological recovery. In this review, we focus on the functions of the Golgi apparatus and its mediated events during neurorestoration.

Keywords: neurodegeneration, Golgi apparatus, neurogenesis, synaptogenesis, angiogenesis

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Received: 16 July 2019
Revised: 08 September 2019
Accepted: 19 September 2019
Published: 09 October 2019
Issue date: September 2019

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© The authors 2019

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This work was supported by the National Natural Science Foundation of China (Grant no. 81471335).

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