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31 August 2020
Open Access
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Published:
31 August 2020
Circadian rhythm and neurodegenerative disorders
Yong Zhang(
)
)
Cite this article:
Werdann M, Zhang Y.
Circadian rhythm and neurodegenerative disorders.
Brain Science Advances,
2020, 6(2): 71-80.
https://doi.org/10.26599/BSA.2020.9050006
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The circadian clock controls daily rhythms in animal physiology, metabolism, and behavior, such as the sleep-wake cycle. Disruption of circadian rhythms has been revealed in many diseases including neurodegenerative disorders. Interestingly, patients with many neurodegenerative diseases often show problems with circadian clocks even years before other symptoms develop. Here we review the recent studies identifying the association between circadian rhythms and several major neurodegenerative disorders. Early intervention of circadian rhythms may benefit the treatment of neurodegeneration.
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Circadian rhythm and neurodegenerative disorders
Yong Zhang(
)
)
Abstract
The circadian clock controls daily rhythms in animal physiology, metabolism, and behavior, such as the sleep-wake cycle. Disruption of circadian rhythms has been revealed in many diseases including neurodegenerative disorders. Interestingly, patients with many neurodegenerative diseases often show problems with circadian clocks even years before other symptoms develop. Here we review the recent studies identifying the association between circadian rhythms and several major neurodegenerative disorders. Early intervention of circadian rhythms may benefit the treatment of neurodegeneration.
Keywords:
circadian rhythms, neurodegenerative diseases, ataxia, dementia
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Publication history
Received: 07 February 2020
Revised: 14 March 2020
Accepted: 21 March 2020
Published:
31 August 2020
Issue date: June 2020
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© The authors 2020
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