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Review Article | Open Access

Advances in Breast Ultrasound Segmentation and Classification

Lijia FuaNa LibZiling LiaocYanping LinaZhaojun LidFan Lie( )
School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, PR China
School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, PR China
Department of Radiology, Chengdu Seventh People's Hospital, Sichuan, PR China
Department of Ultrasound, Children's Hospital of Shanghai, Shanghai Jiao tong University School of Medicine, Shanghai, PR China
Department of Ultrasound, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China
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Abstract

Breast cancer is one of the most prevalent cancers affecting women worldwide. Ultrasound is extensively utilized for clinical screening and diagnosis due to its affordability, absence of radiation, and rapid imaging capability. To enhance diagnostic accuracy, computer-aided diagnosis (CAD) systems have been developed, with segmentation and classification being key techniques. This review systematically examines 62 recent studies on breast ultrasound segmentation and classification, covering various imaging techniques such as B-mode, elastography, 3D ultrasound, contrast-enhanced ultrasound (CEUS), and color Doppler. specifically, we detail the challenges and deep-learning-based methods associated with these modalities. Comparative analysis reveals that current deep learning approaches typically achieve Dice coefficients ranging from 0.79 to 0.91 for segmentation and classification accuracies exceeding 88.2% in multimodal settings. Finally, this article identifies critical research gaps, including data scarcity and model interpretability, and discusses future directions such as multimodal fusion and explainable AI (XAI) to further improve clinical applicability.

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Advanced Ultrasound in Diagnosis and Therapy
Pages 29-41

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Review Status: {{reviewData.commendedNum}} Commended , {{reviewData.revisionRequiredNum}} Revision Required , {{reviewData.notCommendedNum}} Not Commended Under Peer Review

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Cite this article:
Fu L, Li N, Liao Z, et al. Advances in Breast Ultrasound Segmentation and Classification. Advanced Ultrasound in Diagnosis and Therapy, 2026, 10(1): 29-41. https://doi.org/10.26599/AUDT.2026.250056

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Received: 08 December 2025
Revised: 07 January 2026
Accepted: 18 January 2026
Published: 17 March 2026
2576-2508/© AUDT 2026

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed