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Review | Open Access

Breast cancer screening and early diagnosis in Chinese women

Rui Ding1,2,*Yi Xiao1,2,*Miao Mo3Ying Zheng3Yi-Zhou Jiang1,2 ( )Zhi-Ming Shao1,2,4 ( )
Key Laboratory of Breast Cancer in Shanghai, Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
Department of Cancer Prevention, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
Precision Cancer Medicine Center, Fudan University Shanghai Cancer Center, Shanghai 200032, China

*These authors contributed equally to this work.

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Abstract

Breast cancer is the most common malignant tumor in Chinese women, and its incidence is increasing. Regular screening is an effective method for early tumor detection and improving patient prognosis. In this review, we analyze the epidemiological changes and risk factors associated with breast cancer in China and describe the establishment of a screening strategy suitable for Chinese women. Chinese patients with breast cancer tend to be younger than Western patients and to have denser breasts. Therefore, the age of initial screening in Chinese women should be earlier, and the importance of screening with a combination of ultrasound and mammography is stressed. Moreover, Chinese patients with breast cancers have several ancestry-specific genetic features, and aiding in the determination of genetic screening strategies for identifying high-risk populations. On the basis of current studies, we summarize the development of risk-stratified breast cancer screening guidelines for Chinese women and describe the significant improvement in the prognosis of patients with breast cancer in China.

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Cancer Biology & Medicine
Pages 450-467

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Cite this article:
Ding R, Xiao Y, Mo M, et al. Breast cancer screening and early diagnosis in Chinese women. Cancer Biology & Medicine, 2022, 19(4): 450-467. https://doi.org/10.20892/j.issn.2095-3941.2021.0676

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Received: 17 December 2021
Accepted: 21 February 2022
Published: 01 April 2022
©2022 Cancer Biology & Medicine.

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