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Letter to the Editor | Open Access

A novel CRB1 variant presenting as Leber congenital amaurosis-8 with angle-closure glaucoma in a Chinese family

Gong Chen1,2, Zhi-Ruo Wang1,2, Cong Zhao1,2, Hui-Hui Chen1,2,3( ), Jing-Ming Shi1,2( )
Department of Ophthalmology, the Second Xiangya Hospital of Central South University, Changsha 410000, Hunan Province, China
Hunan Clinical Research Center of Ophthalmic Disease, Changsha 410011, Hunan Province, China
Clinical Immunology Research Center of Central South University, Changsha 410000, Hunan Province, China
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International Journal of Ophthalmology
Volume 19 Issue 3,
March 2026
Pages 630-633
DOI: 10.18240/ijo.2026.03.25

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Chen G, Wang Z-R, Zhao C, et al. A novel CRB1 variant presenting as Leber congenital amaurosis-8 with angle-closure glaucoma in a Chinese family. International Journal of Ophthalmology, 2026, 19(3): 630-633. https://doi.org/10.18240/ijo.2026.03.25

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Received: 21 April 2025
Accepted: 11 June 2025
Published: 18 March 2026
© 2026 International Journal of Ophthalmology Press

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).