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Review Article | Publishing Language: Chinese | Open Access

Bleeding after tooth extraction in patients receiving anticoagulation/antiplatelet therapy

Jinxia HUANGHaitao SHIJian PAN( )
State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Oral Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
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Abstract

Tooth extraction in patients receiving anticoagulation/antiplatelet therapy is often considered contraindicated by many oral and maxillofacial surgeons because of a higher risk of postoperative bleeding. Multiple factors contribute to postoperative bleeding, but there is no consensus. Based on recent literature, this article reviews factors related to bleeding after tooth extraction in patients receiving anticoagulation/antiplatelet therapy. The literature review indicates that patients taking antiplatelet drugs have a lower postoperative bleeding risk than patients taking anticoagulant drugs. Prescription of anticoagulants together with non-steroidal anti-inflammatory drugs, selective serotonin inhibitors or serotonin-norepinephrine inhibitors increases the risk of bleeding, so does preoperative antibiotic use increase. In addition, systemic diseases such as diabetes, history of infection at the extraction site, and greater surgical trauma are associated with a higher risk of postoperative bleeding. At present, it is generally believed that it is safe and feasible to use different hemostatic measures after tooth extraction and to rationally apply different hemostatic measures after surgery. More prospective controlled trials are needed in the future to establish an assessment system for patients undergoing anticoagulation/antiplatelet therapy under different conditions during tooth extraction.

CLC number: R78 Document code: A Article ID: 2096-1456(2021)06-0417-05

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Journal of Prevention and Treatment for Stomatological Diseases
Pages 417-421

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Review Status: {{reviewData.commendedNum}} Commended , {{reviewData.revisionRequiredNum}} Revision Required , {{reviewData.notCommendedNum}} Not Commended Under Peer Review

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Cite this article:
HUANG J, SHI H, PAN J. Bleeding after tooth extraction in patients receiving anticoagulation/antiplatelet therapy. Journal of Prevention and Treatment for Stomatological Diseases, 2021, 29(6): 417-421. https://doi.org/10.12016/j.issn.2096-1456.2021.06.010

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Received: 02 March 2020
Revised: 09 December 2020
Published: 20 June 2021
© 2021 by Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases