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Review Article | Publishing Language: Chinese | Open Access

Research progress of probiotics in the prevention and treatment of oral infectious diseases

Jiatong LI1Xuedong ZHOU1Xin XU1Yan WANG2( )
State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Deparment of Pediatric Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
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Abstract

Oral infectious diseases include caries, periodontal disease, halitosis, candidiasis albicans and so on. Over the past few decades, probiotics have mainly been studied in the field of the gastrointestinal tract. In recent years, probiotics have begun to be used in the prevention and treatment of various oral diseases and have become a new field in the research of oral disease prevention and control technology. This paper reviews the research progress of probiotics applied in the prevention and treatment of various oral infectious diseases. A review of the literature shows that probiotics can prevent and cure dental caries by inhibiting the growth of Streptococcus mutans and competing with them for nutrition and attachment sites. Probiotics not only inhibit periodontal pathogens and reduce the production of sulfide, they also regulate the body′s immune function to alleviate halitosis and periodontal inflammation. Probiotics can inhibit periodontal caries by inhibiting them. Probiotics can inhibit them mycelial growth of Candida albicans and interfere with its adherence, thus playing a role in the prevention and treatment of oral candidiasis. Current studies have shown that pro-biotics play an auxiliary role in the treatment of caries, periodontitis, halitosis and oral candidiasis. However, the mechanism of probiotics in the prevention and treatment of oral infectious diseases is still unclear, and the safety of probiotics remains to be further studied. In the future, oral probiotics should be studied with reference to intestinal probiotics to better work to prevent and treat oral diseases.

CLC number: R78 Document code: A Article ID: 2096-1456(2019)09-0598-04

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Journal of Prevention and Treatment for Stomatological Diseases
Pages 598-602

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Cite this article:
LI J, ZHOU X, XU X, et al. Research progress of probiotics in the prevention and treatment of oral infectious diseases. Journal of Prevention and Treatment for Stomatological Diseases, 2019, 27(9): 598-602. https://doi.org/10.12016/j.issn.2096-1456.2019.09.010

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Received: 09 September 2018
Revised: 26 April 2019
Published: 20 September 2019
© 2019 by Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases