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Review | Open Access

The 2023 yearbook of Neurorestoratology

Hongyun Huanga( ), John R. Bachb, Hari Shanker Sharmac, Lin Chend, Ping Wue, Anna Sarnowskaf, Ali Otomg, Mengzhou Xueh, Hooshang Saberii, Xijing Hej, Ziad Alhawamdehk, Damien Kufflerl, Jianzhong Hum, Dario Siniscalcon, Edgardo O. Alvarezo, Mingchang Lip, Paul R. Sanbergq
Cell therapy Center, Beijing Hongtianji Neuroscience Academy, Beijing 100143, China
Department of Physical Medicine and Rehabilitation, Center for Ventilator Management Alternatives, University Hospital, Rutgers University – New Jersey Medical School, Newark 07102, NJ, USA
Experimental Central Nervous System Injury & Repair, Anesthesiology & Intensive Care Medicine, Department of Surgical Sciences, University Hospital, Uppsala University, SE-75185 Uppsala, Sweden
Department of Neurosurgery, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100007, China
Department of Neurobiology, Cell Biology & Anatomy, University of Texas Medical Branch, Galveston 77555-0654, TX, USA
Translational Platform for Regenerative Medicine, Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw 02-106, Poland
Department of Rehabilitation Medicine, Jordan University Hospital, Amman 11183, Jordan
Department of Cerebrovascular Diseases, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450001, Henan, China
Department of Neurosurgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran 1419733141, Iran
Xi'an International Rehabilitation Medical Center Hospital, Xi'an 710119, Shaanxi, China
School of Medicine, The University of Jordan, Amman 11942, Jordan
Institute of Neurobiology, University of Puerto Rico, San Juan PR 00901, Puerto Rico
Department of Spine Surgery, Xiangya Hospital of Central South University, Changsha 410008, Hunan, China
Department of Experimental Medicine, University of Campania “Luigi Vanvitelli”, Naples 80138, Italy
Laboratory of epigenetics and Neuropharmacology, faculty of Medical Sciences, Sede San Luis Catholic Cuyo University, San Luis 5700, Argentina
Department of Neurosurgery, Renmin Hospital of Wuhan university, Wuhan 430060, Hubei, China
Center of Excellence for Aging & Brain Repair, Department of Neurosurgery & Brain Repair, Morsani College of Medicine, University of South Florida, Tampa 33612, FL, USA
Show Author Information

Abstract

Remarkable advancements have been made in understanding the pathogenesis of Alzheimer's disease, Parkinson's disease, and other neurological disease; in our depth of understanding neurorestorative mechanisms such as anti-inflammatory processes, immune regulation, neuromodulation, neovascularization/neural repair, and neuroprotection; and in clinical neurorestorative treatments. Multiple types of cell therapies have been reported, with some positive outcomes. Diverse forms of neurostimulation and neuromodulation as well as brain–computer interfaces have shown good therapeutic outcomes in clinical applications. Further, therapeutic neurorestorative surgery and pharmaceutic therapy have been very impressive. These fundamental achievements are helpful for understanding the pathogenesis of neurological diseases and the mechanisms of neurorestoration. Patients with neurological impairments have benefited from therapeutic progress, but some of these therapies still require confirmation in higher-level randomized clinical trials.

Keywords

Pathogenesis of neurological diseasesNeurorestorative mechanismsClinical neurorestorative treatmentsCell therapyNeurostimulation and neuromodulationBrain-computer interfaces

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Journal of Neurorestoratology
Volume 12 Issue 3,
September 2024
Article number: 100136
DOI: 10.1016/j.jnrt.2024.100136
Cite this article:
Huang H, Bach JR, Sharma HS, et al. The 2023 yearbook of Neurorestoratology. Journal of Neurorestoratology, 2024, 12(3): 100136. https://doi.org/10.1016/j.jnrt.2024.100136

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Received: 24 March 2024
Revised: 07 May 2024
Accepted: 08 May 2024
Published: 13 June 2024
© 2024 The Authors.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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