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Review | Open Access

Integrative insights into cerebrometabolic disease: Understanding, management, and future prospects

Gaili YanaXiangyu Zhanga,bYang Liua,bPingping Guoa,bYuanyuan LiuaXin LiaV. Wee Yongc( )Mengzhou Xuea,b( )
Department of Cerebrovascular Diseases, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450001, Henan, China
Academy of Medical Science, Zhengzhou University, Zhengzhou 450001, Henan, China
Hotchkiss Brain Institute and Department of Clinical Neurosciences, University of Calgary, Calgary T2N 1N4, Alberta, Canada
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Abstract

Cerebrovascular disease is among the most common causes of permanent disability and mortality in adults and places immense pressure on health care resources. Metabolic diseases caused by susceptibility genes and unhealthy lifestyle play a key role in the development of cerebrovascular disease. Cardiometabolic disease is now well established and rapidly evolving. Cardiometabolic medicine, which considers metabolic issues and cardiovascular disease as an integrated whole, has been implemented in many countries worldwide. However, integrated management of metabolic risk factors and cerebrovascular disease is still in the initial stages. In this minireview, we propose a concept and definition of cerebrometabolic disease, describe its possible pathogenesis, summarize the recently proposed integrative therapeutic approach, and discuss future developments as well as challenges, with the aim of promoting a deeper understanding and integrated management of metabolic issues and cerebrovascular disease.

Journal of Neurorestoratology
Article number: 100107
Cite this article:
Yan G, Zhang X, Liu Y, et al. Integrative insights into cerebrometabolic disease: Understanding, management, and future prospects. Journal of Neurorestoratology, 2024, 12(2): 100107. https://doi.org/10.1016/j.jnrt.2024.100107

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Received: 20 December 2023
Revised: 20 January 2024
Accepted: 24 January 2024
Published: 29 February 2024
© 2024 The Author(s).

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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