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Review | Open Access

An overview of the recent developments in biodegradable Mg-Zn alloy

Manas Ranjan Sahu( )Akiko Yamamoto
Research Centre for Macromolecules and Biomaterials, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan
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Abstract

The increasing interest in Mg-Zn binary alloys as temporary implant materials is attributed to their outstanding biocompatibility, biodegradability, and favourable mechanical properties. However, their application is constrained by high degradation rates in the physiological environment, resulting in the release of hydrogen gas and a rapid decline in mechanical properties. Additionally, the material’s biocompatibility is contingent upon its degradability. Researchers have demonstrated that addressing these issues is possible through strategies such as controlling Zn content, employing thermo-mechanical processing to achieve suitable microstructures, and applying surface coatings. This manuscript provides a comprehensive review of published literature on Mg-Zn alloys, exploring the challenges and outlining future research directions in this field.

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Journal of Magnesium and Alloys
Pages 486-509

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Cite this article:
Ranjan Sahu M, Yamamoto A. An overview of the recent developments in biodegradable Mg-Zn alloy. Journal of Magnesium and Alloys, 2025, 13(2): 486-509. https://doi.org/10.1016/j.jma.2025.01.011

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Received: 08 December 2024
Revised: 10 January 2025
Accepted: 14 January 2025
Published: 03 February 2025
© 2025 Chongqing University.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/) Peer review under responsibility of Chongqing University