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Commentary | Open Access

Comment on “Clinical outcomes and histologic findings of patients with hepatocellular carcinoma with durable partial response or durable stable disease after receiving atezolizumab plus bevacizumab”

Binghua Lia,1Qiang Wangb,1Weiwei HucHuan LiaPeng YanaYajuan CaoaDecai Yua( )
Division of Hepatobiliary and Transplantation Surgery, Department of General Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China
Department of Clinical Science, Intervention and Technology (CLINTEC), Division of Medical Imaging and Technology, Karolinska Institutet, Stockholm 14186, Sweden
Center for New Drug Safety Evaluation and Research, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, China

1 Co-first authors, with equal contributions.

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References

[1]

Shen YC, Liu TH, Nicholas A, et al. Clinical outcomes and histologic findings of patients with hepatocellular carcinoma with durable partial response or durable stable disease after receiving atezolizumab plus bevacizumab. J Clin Oncol 2024: JCO2400645. https://doi.org/10.1200/JCO.24.00645.

[2]

Finn RS, Qin S, Ikeda M, et al. Atezolizumab plus bevacizumab in unresectable hepatocellular carcinoma. N Engl J Med 2020;382(20):1894–905. https://doi.org/10.1056/NEJMoa1915745.

[3]

Donne R, Lujambio A. The liver cancer immune microenvironment: therapeutic implications for hepatocellular carcinoma. Hepatology 2023;77(5):1773–96. https://doi.org/10.1002/hep.32740.

[4]
European Medicines Agency. Guideline on adjustment for baseline covariates in clinical trials. The Netherlands: European Medicines Agency; 2015. Available online: https://www.ema.europa.eu/en/adjustment-baseline-covariates-clinical-trials-scientific-guideline.
[5]

Borcoman E, Kanjanapan Y, Champiat S, et al. Novel patterns of response under immunotherapy. Ann Oncol 2019;30(3):385–96. https://doi.org/10.1093/annonc/mdz003.

[6]

Murad MH, Sultan S, Haffar S, et al. Methodological quality and synthesis of case series and case reports. BMJ Evid Based Med 2018;23(2):60–3. https://doi.org/10.1136/bmjebm-2017-110853.

[7]

Xu B, Dong SY, Bai XL, et al. Tumor radiomic features on pretreatment MRI to predict response to lenvatinib plus an anti-PD-1 antibody in advanced hepatocellular carcinoma: a multicenter study. Liver Cancer 2022;12(3):262–76. https://doi.org/10.1159/000528034.

[8]

Iwamoto H, Shimose S, Niizeki T, et al. Clinical significance of the discrepancy between radiological findings and biochemical responses in atezolizumab plus bevacizumab for hepatocellular carcinoma. Clin Mol Hepatol 2022;28(3):575–9. https://doi.org/10.3350/cmh.2022.0047.

[9]

Sato S, Aoki T, Matsumoto T, et al. Pathological complete response of hepatocellular carcinoma confirmed by conversion hepatectomy following atezolizumab plus bevacizumab therapy: a case report and literature review. Clin J Gastroenterol 2024;17(2):292–9. https://doi.org/10.1007/s12328-023- 01895-7.

[10]

Li B, Wen J, Xu Z, et al. Comprehensive analysis of transcriptomic biomarkers for predicting response to atezolizumab plus bevacizumab immunotherapy in hepatocellular carcinoma. Clin Mol Hepatol 2024. https://doi.org/10.3350/cmh.2024.0628.

iLIVER
Article number: 100130
Cite this article:
Li B, Wang Q, Hu W, et al. Comment on “Clinical outcomes and histologic findings of patients with hepatocellular carcinoma with durable partial response or durable stable disease after receiving atezolizumab plus bevacizumab”. iLIVER, 2024, 3(4): 100130. https://doi.org/10.1016/j.iliver.2024.100130

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Received: 21 September 2024
Revised: 14 October 2024
Accepted: 16 October 2024
Published: 07 November 2024
© 2024 The Author(s). Tsinghua University Press.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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