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Commentary | Open Access

Increased attention to women with drug-induced liver injury: Risk factors and early intervention

Xiaoru Suna,bXinrong ZhangcMuyun Liua,b( )
Department of Infectious Disease, NO. 905 Hospital of PLA Navy Affiliated to Naval Medical University, Shanghai 200052, China
Department of Gastroenterology, National Clinical Research Center for Digestive Diseases, Changhai Hospital, National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai 200433, China
Division of Gastroenterology and Hepatology, Stanford University Medical Center, Palo Alto 94305, CA, USA
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Abstract

A recent study by Xiong Yu-Ting and colleagues has unveiled the clinical characteristics and risk factors of acute drug-induced liver injury (DILI). Upon reading the article, we found that there are some differences between female and male patients with DILI in terms of clinical and pathological features, especially in the number of patients, the degree of liver inflammation, and the risk of autoimmune liver disease. Therefore, it is necessary to pay attention to female patients with DILI and their outcomes, and to intervene appropriately in advance. This article analyzes the reasons for the differences between female and male patients with DILI and makes recommendations for patient prognosis.

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iLIVER
Article number: 100125
Cite this article:
Sun X, Zhang X, Liu M. Increased attention to women with drug-induced liver injury: Risk factors and early intervention. iLIVER, 2024, 3(4): 100125. https://doi.org/10.1016/j.iliver.2024.100125

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Received: 10 September 2024
Revised: 04 October 2024
Accepted: 16 October 2024
Published: 30 October 2024
© 2024 Tsinghua University Press.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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