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iLIVER 2022, 1(4): 237-244 https://doi.org/10.1016/j.iliver.2022.10.003
Review | Open Access | Issue | Published: 08 November 2022

Advances in magnetic particle imaging and perspectives on liver imaging

Show Author's Information Wei Lia,b,1,  Xiaohua Jiab,1,  Lin Yinb,c,d,1,  Zhiyun Yanga,  Hui Huib,c,d,  Jianlin Lie,  Wenhui Huanga,  Jie Tianb,c,f,g( ),  Shuixing Zhanga( )
Department of Radiology, The First Affiliated Hospital, Jinan University, No.613, Huangpu West Road, Tianhe District, Guangzhou, 510627, Guangdong, China
CAS Key Laboratory of Molecular Imaging, Institute of Automation, Beijing, 100190, China
Beijing Key Laboratory of Molecular Imaging, Beijing, 100190, China
University of Chinese Academy of Sciences, Beijing, 100080, China
School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, China
Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, School of Engineering Medicine, Beihang University, Beijing, 100083, China
Zhuhai Precision Medical Center, Zhuhai People's Hospital, Affiliated with Jinan University, Zhuhai, 519000, China

1 These authors contributed equally to this work.

Keywords:
Magnetic particle imaging, Liver imaging, SPIO
Cite this article:
Li W, Jia X, Yin L, et al. Advances in magnetic particle imaging and perspectives on liver imaging. iLIVER, 2022, 1(4): 237-244. https://doi.org/10.1016/j.iliver.2022.10.003
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Abstract Full text About this article

Magnetic particle imaging (MPI) is an emerging technique to visualize the spatial distribution of superparamagnetic iron oxide with high temporal–spatial resolution, high sensitivity, unlimited image depth, and true quantitative information. MPI is based on the nonlinear response of superparamagnetic iron oxide in an alternating magnetic field without tissue background noise. It is a promising imaging modality for various applications, including vascular imaging, cell tracking, tumor imaging, and catheter navigation. Many applications of liver imaging could be improved or created with MPI. In this review, we cover the principle and construction of MPI, we evaluate the features and advantages of MPI with relation to its own rationale and via comparison with other imaging modalities, and we review MPI liver imaging applications with a view toward assisting hepatic researchers in drawing inspiration.


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About this article

Advances in magnetic particle imaging and perspectives on liver imaging

Show Author's information Wei Lia,b,1, Xiaohua Jiab,1, Lin Yinb,c,d,1, Zhiyun Yanga, Hui Huib,c,d, Jianlin Lie, Wenhui Huanga, Jie Tianb,c,f,g( ), Shuixing Zhanga( )
Department of Radiology, The First Affiliated Hospital, Jinan University, No.613, Huangpu West Road, Tianhe District, Guangzhou, 510627, Guangdong, China
CAS Key Laboratory of Molecular Imaging, Institute of Automation, Beijing, 100190, China
Beijing Key Laboratory of Molecular Imaging, Beijing, 100190, China
University of Chinese Academy of Sciences, Beijing, 100080, China
School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, China
Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, School of Engineering Medicine, Beihang University, Beijing, 100083, China
Zhuhai Precision Medical Center, Zhuhai People's Hospital, Affiliated with Jinan University, Zhuhai, 519000, China

1 These authors contributed equally to this work.

Abstract

Magnetic particle imaging (MPI) is an emerging technique to visualize the spatial distribution of superparamagnetic iron oxide with high temporal–spatial resolution, high sensitivity, unlimited image depth, and true quantitative information. MPI is based on the nonlinear response of superparamagnetic iron oxide in an alternating magnetic field without tissue background noise. It is a promising imaging modality for various applications, including vascular imaging, cell tracking, tumor imaging, and catheter navigation. Many applications of liver imaging could be improved or created with MPI. In this review, we cover the principle and construction of MPI, we evaluate the features and advantages of MPI with relation to its own rationale and via comparison with other imaging modalities, and we review MPI liver imaging applications with a view toward assisting hepatic researchers in drawing inspiration.

Keywords: Magnetic particle imaging, Liver imaging, SPIO

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Publication history
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Acknowledgements
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Publication history

Received: 22 August 2022
Revised: 08 October 2022
Accepted: 18 October 2022
Published: 08 November 2022
Issue date: December 2022

Copyright

© 2022 The Author(s). Published by Elsevier Ltd on behalf of Tsinghua University Press.

Acknowledgements

The authors would like to acknowledge the instrumental and technical support of Multimodal Biomedical Imaging Experimental Platform, Institute of Automation, Chinese Academy of Sciences.

Rights and permissions

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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