AI Chat Paper
Note: Please note that the following content is generated by AMiner AI. SciOpen does not take any responsibility related to this content.
{{lang === 'zh_CN' ? '文章概述' : 'Summary'}}
{{lang === 'en_US' ? '中' : 'Eng'}}
Chat more with AI
Powered by AMiner. Clicking this button will take you away from SciOpen.
Home Genes & Diseases Article
PDF (1.4 MB)
Cite
EndNote(RIS) BibTeX
Collect
Submit Manuscript AI Chat Paper
Show Outline
Outline
Show full outline
Hide outline
Outline
Show full outline
Hide outline
Rapid Communication | Open Access

Actin polymerization regulates the osteogenesis of hASCs by influencing α-tubulin expression and Eg5 activity

Tingyu Fana,1, Wenqing Liua,1, Rongmei Qua, Jinhui Zhua, Yulian Shia, Jiaxuan Liua, Xiangtian Lia, Zhitao Zhoub, Yunbing Changc( ), Jun Ouyanga( ), Jingxing Daia( )
Guangdong Provincial Key Laboratory of Digital Medicine and Biomechanics & Guangdong Engineering Research Center for Translation of Medical 3D Printing Application & National Virtual & Reality Experimental Education Center for Medical Morphology (Southern Medical University) & National Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong 510515, China
Central Laboratory, Southern Medical University, Guangzhou, Guangdong 510515, China
Department of Spine Surgery, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong 510515, China

1 These authors contributed equally to this work.

Peer review under responsibility of Chongqing Medical University.

Show Author Information

References

1

Koushik TM, Miller CM, Antunes E. Bone tissue engineering scaffolds: function of multi-material hierarchically structured scaffolds. Adv Healthcare Mater. 2023;12(9):e2202766.
Crossref Google Scholar
2

Li W, Liu Y, Zhang P, et al. Tissue-engineered bone immobilized with human adipose stem cells-derived exosomes promotes bone regeneration. ACS Appl Mater Interfaces. 2018;10(6):5240–5254.
Crossref Google Scholar
3

Garcia-Saez I, Skoufias DA. Eg5 targeting agents: from new anti-mitotic based inhibitor discovery to cancer therapy and resistance. Biochem Pharmacol. 2021;184:114364.
Crossref Google Scholar
4

Zheng J, Tan Y, Liu X, et al. NAT10 regulates mitotic cell fate by acetylating Eg5 to control bipolar spindle assembly and chromosome segregation. Cell Death Differ. 2022;29(4):846–860.
Crossref Google Scholar
5

Guo W, Sun S, Sanchez JE, et al. Using a comprehensive approach to investigate the interaction between Kinesin-5/Eg5 and the microtubule. Comput Struct Biotechnol J. 2022;20:4305–4314.
Crossref Google Scholar
Genes & Diseases
Volume 12 Issue 2,
March 2025
Article number: 101380
DOI: 10.1016/j.gendis.2024.101380
Cite this article:
Fan T, Liu W, Qu R, et al. Actin polymerization regulates the osteogenesis of hASCs by influencing α-tubulin expression and Eg5 activity. Genes & Diseases, 2025, 12(2): 101380. https://doi.org/10.1016/j.gendis.2024.101380

67

Views

2

Downloads

0

Crossref

0

Web of Science

0

Scopus

0

CSCD

Altmetrics
Received: 15 October 2023
Published: 26 July 2024
© 2024 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Return