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Rapid Communication | Open Access

A novel nested gene Aff3ir participates in vascular remodeling by enhancing endothelial cell differentiation in mice

Yue Zhaoa,b,c,1, Mazdak Ehteramyanb,1, Yi Lib,1, Xuefeng Baib, Lei Huanga,b, Yingtang Gaod,e, Angshumonik Angbohangb, Xiaoping Yangb, Steven Lynhamb, Andriana Margaritif, Ajay M. Shahb, Yaling Taog, Ting Caig, Tong Lia,c,d,e( ), Min Zhangb( ), Lingfang Zengb( )
Department of Heart Center, Nankai University Affiliated Third Center Hospital, Tianjin 300170, China
School of Cardiovascular and Metabolic Medicine and Sciences, King’s College London British Heart Foundation Centre of Excellence, Faculty of Life Science and Medicine, King’s College London, London SE5 9NU, United Kingdom
School of Medicine, Nankai University, Tianjin 300071, China
Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases, Nankai University Affiliated Third Center Hospital, Tianjin 300170, China
Tianjin Institute of Hepatobiliary Disease, Nankai University Affiliated Third Centre Hospital, Tianjin 300170, China
Wellcome-Wolfson Institute for Experimental Medicine, Queen’s University Belfast, Belfast BT9 7BL, United Kingdom
Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo, Zhejiang 315010, China

1 These authors contributed equally to this work.

Peer review under responsibility of Chongqing Medical University.

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Genes & Diseases
Volume 12 Issue 2,
March 2025
Article number: 101339
DOI: 10.1016/j.gendis.2024.101339
Cite this article:
Zhao Y, Ehteramyan M, Li Y, et al. A novel nested gene Aff3ir participates in vascular remodeling by enhancing endothelial cell differentiation in mice. Genes & Diseases, 2025, 12(2): 101339. https://doi.org/10.1016/j.gendis.2024.101339

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Received: 07 January 2024
Published: 27 May 2024
© 2024 The Authors.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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