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Rapid Communication | Open Access

SIK2 promotes malignant features of human osteosarcoma via up-regulating MMP2 and β-catenin expression

Yutong Wanga,1Yulan Yaob,1Sen KoucShanshan WangcJuntao SongdSiqi YangcHongwei Wange( )Yunliang Wangb,c( )
School of Public Health and Laboratory of Qilu Medical University, Zibo, Shandong 255300, China
Department of Neurology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450014, China
Department of Neurology, Zibo 148 Hospital, Zibo, Shandong 255300, China
Department of Oncology and Hematology, Zibo 148 Hospital, Zibo, Shandong 255300, China
School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu 211166, China

Peer review under responsibility of Chongqing Medical University.

1 Yutong Wang and Yulan Yao are co-first authors.

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Genes & Diseases
Article number: 101325

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Cite this article:
Wang Y, Yao Y, Kou S, et al. SIK2 promotes malignant features of human osteosarcoma via up-regulating MMP2 and β-catenin expression. Genes & Diseases, 2025, 12(2): 101325. https://doi.org/10.1016/j.gendis.2024.101325

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Received: 06 December 2023
Published: 26 June 2024
© 2024 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).