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Rapid Communication | Open Access

BBOX1, LACC1, MMP7 and SSTR1 as common predictors in obesity and non-alcoholic fatty liver disease

Chaoyuan Huanga,b,1Guoming Chenc,1Dongqiang LuodJiyuan ZhengeNan ZhongfDanyun LigYang LuoePeizhen HuangeNing WangcYibin Fengc( )Yiyuan Zhengh( )
Department of Gastroenterology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510120, China
Department of Gastroenterology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong 510120, China
School of Chinese Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR 999077, China
Clifford Hospital, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 511495, China
The First School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510405, China
The University of Edinburgh, Edinburgh EH8 9LQ, United Kingdom
Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
Department of Gastroenterology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China

1 These authors contributed equally to this work and are co-first authors.

Peer review under responsibility of Chongqing Medical University.

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References

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Sheka AC, Adeyi O, Thompson J, Hameed B, Crawford PA, Ikramuddin S. Nonalcoholic steatohepatitis: a review. JAMA. 2020;323(12):1175-1183.

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Dietrich P, Hellerbrand C. Non-alcoholic fatty liver disease, obesity and the metabolic syndrome. Best Pract Res Clin Gastroenterol. 2014;28(4):637-653.

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Grzechocińska B, Dąbrowski FA, Sierdzinski J, Cyganek A, Wielgoś M. The association between serum metalloproteinase concentration, obesity, and hormone levels in reproductive-aged women. Endokrynol Pol. 2019;70(1):49-56.

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Kotronen A, Yki-Järvinen H. Fatty liver: a novel component of the metabolic syndrome. Arterioscler Thromb Vasc Biol. 2008;28(1):27-38.

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Rigault C, Le Borgne F, Tazir B, Benani A, Demarquoy J. A high-fat diet increases L-carnitine synthesis through a differential maturation of the Bbox1 mRNAs. Biochim Biophys Acta. 2013;1831(2):370-377.

Genes & Diseases
Article number: 101310
Cite this article:
Huang C, Chen G, Luo D, et al. BBOX1, LACC1, MMP7 and SSTR1 as common predictors in obesity and non-alcoholic fatty liver disease. Genes & Diseases, 2025, 12(2): 101310. https://doi.org/10.1016/j.gendis.2024.101310

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Received: 28 January 2023
Published: 24 April 2024
© 2024 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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