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Rapid Communication | Open Access

Factor analysis and subtyping significance of CTNNB1 gene mutation detection in adamantinomatous craniopharyngioma

Huarong Zhanga,c,1Chaohu Wanga,c,1Jun Fana,c,1Rongrong Guoa,b,cQianchao Zhua,cJun Pana,cJunxiang Penga,cZhiyong Wud( )Songtao Qia,c( )Yi Liua,c( )
Department of Neurosurgery, Institute of Brain Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China
The First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong 510515, China
The Laboratory for Precision Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China
College of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong 510515, China

Peer review under responsibility of Chongqing Medical University.

1 These authors are co-first authors and contributed equally to this work.

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References

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Müller HL, Merchant TE, Warmuth-Metz M, Martinez-Barbera JP, Puget S. Craniopharyngioma. Nat Rev Dis Prim. 2019;5(1):75.

2

Hölsken A, Sill M, Merkle J, et al. Adamantinomatous and papillary craniopharyngiomas are characterized by distinct epigenomic as well as mutational and transcriptomic profiles. Acta Neuropathol Commun. 2016;4:20.

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Oikonomou E, Barreto DC, Soares B, De Marco L, Buchfelder M, Adams EF. Beta-catenin mutations in craniopharyngiomas and pituitary adenomas. J Neuro Oncol. 2005;73(3):205–209.

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Wang CH, Qi ST, Fan J, et al. Identification of tumor stem-like cells in admanatimomatous craniopharyngioma and determination of these cells’ pathological significance. J Neurosurg. 2019;133(3):664–674.

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Apps JR, Stache C, Gonzalez-Meljem JM, et al. CTNNB1 mutations are clonal in adamantinomatous craniopharyngioma. Neuropathol Appl Neurobiol. 2020;46(5):510–514.

Genes & Diseases
Article number: 101188
Cite this article:
Zhang H, Wang C, Fan J, et al. Factor analysis and subtyping significance of CTNNB1 gene mutation detection in adamantinomatous craniopharyngioma. Genes & Diseases, 2024, 11(6): 101188. https://doi.org/10.1016/j.gendis.2023.101188

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Received: 19 July 2023
Published: 30 November 2023
© 2023 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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