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Rapid Communication | Open Access

Single-cell analyses revealed key tumor-infiltrating myeloid cell subsets associated with clinical outcomes in different subtypes of breast cancer

Dingjie Wua,1Si Chena,1Yijin LiubBowen YangcRuixin LibFeng JinbFan Yaob( )Yue Fanga( )
Department of Microbial and Biochemical Pharmacy, School of Pharmacy, China Medical University, Shenyang, Liaoning 110122, China
Department of Breast Surgery and Surgical Oncology, Research Unit of General Surgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110000, China
Department of Medical Oncology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110000, China

1 These authors contributed equally to this work.

Peer review under responsibility of Chongqing Medical University.

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References

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Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA A Cancer J Clin. 2021;71(3):209–249.

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Cheng S, Li Z, Gao R, et al. A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells. Cell. 2021;184(3):792–809.e23.

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Zhang Q, He Y, Luo N, et al. Landscape and dynamics of single immune cells in hepatocellular carcinoma. Cell. 2019;179(4):829–845.e20.

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Mukaida N, Sasaki SI, Baba T. CCL4 signaling in the tumor microenvironment. Adv Exp Med Biol. 2020;1231:23–32.

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Dwyer DF, Barrett NA, Austen KF, Consortium IGP. Expression profiling of constitutive mast cells reveals a unique identity within the immune system. Nat Immunol. 2016;17(7):878–887.

Genes & Diseases
Article number: 101185
Cite this article:
Wu D, Chen S, Liu Y, et al. Single-cell analyses revealed key tumor-infiltrating myeloid cell subsets associated with clinical outcomes in different subtypes of breast cancer. Genes & Diseases, 2024, 11(6): 101185. https://doi.org/10.1016/j.gendis.2023.101185

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Received: 24 June 2023
Published: 30 November 2023
© 2023 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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