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Research Article | Open Access

Assessment of effectiveness of oral supplementation of isolated fiber of carrot on metabolic parameters in mature rats

Maria Rosana Ramireza,b( ), Debora Manualeb,c,d, Juan Carlos Yorib,c,d
Instituto Universitario de Ciencias de la Salud, Fundación Barceló, CONICET, Centeno 710, CP 3340, Santo Tome, Corrientes, Argentina
Consejo Nacional de Investigaciones Científicas Técnicas (CONICET), Buenos Aires C1033AAJ, Argentina
Instituto de Investigaciones en Catálisis y Petroquímica (INCAPE) FIQ-UNL-CONICET, Parque Tecnológico Litoral Centro 3000, Santa Fe, Argentina
Facultad de Ingeniería Química, Universidad nacional del Litoral 3000, Santa Fe, Argentina

Peer review under responsibility of KeAi Communications Co., Ltd.

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Abstract

The present study was conducted to evaluate the metabolic effects of isolated fiber of carrot supplementation in rats. Physicochemical properties of fiber were determined. The groups were as follows: animals fed a standard diet, control group; high fiber supplementation (70 mg); low fiber supplementation (35 mg); for 12 weeks. Blood samples were collected at the time of sacrifice. The weights of heart, liver, kidneys and spleen of the experimental rats with respect to body weight were recorded. Commercial kits were used to determine serum glucose concentration, lipid profile (cholesterol, HDL-cholesterol, triglycerides), and the two main aminotransferases glutamic-oxalacetic transaminase (GOT)/glutamate-pyruvate transaminase (GPT). A histopathological assay was performed on the heart, liver, and spleen tissues of animals. Supplementation with fiber favors weight loss in female ((242.03 ± 23.73)−(197.81 ± 10.45) g); and male rats ((262.50 ± 32.21)−(213.96 ± 12.56) g) and induces a decrease in glucose levels in the supplemented animals. With the exception of total high-density lipoprotein cholesterol, the other lipid fractions decrease significantly in rats supplemented. Fiber supplementation did not induce changes in the dissected organs of the supplemented animals. In conclusion supplementation of fiber, improves glucose control, lower plasma lipid concentrations and reduced body weight in normal rats.

Keywords

Carrot fiberOral supplementationAnimal studies

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Food Science and Human Wellness
Volume 12 Issue 6,
November 2023
Pages 2022-2028
DOI: 10.1016/j.fshw.2023.03.016
Cite this article:
Ramirez MR, Manuale D, Yori JC. Assessment of effectiveness of oral supplementation of isolated fiber of carrot on metabolic parameters in mature rats. Food Science and Human Wellness, 2023, 12(6): 2022-2028. https://doi.org/10.1016/j.fshw.2023.03.016

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Received: 05 January 2021
Revised: 02 February 2021
Accepted: 21 April 2021
Published: 04 April 2023
© 2023 Beijing Academy of Food Sciences.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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