AI Chat Paper
Note: Please note that the following content is generated by AMiner AI. SciOpen does not take any responsibility related to this content.
{{lang === 'zh_CN' ? '文章概述' : 'Summary'}}
{{lang === 'en_US' ? '中' : 'Eng'}}
Chat more with AI
Powered by AMiner. Clicking this button will take you away from SciOpen.
Home Biophysics Reports Article
PDF (676 KB)
Cite
EndNote(RIS) BibTeX
Collect
Submit Manuscript AI Chat Paper
Show Outline
Outline
Show full outline
Hide outline
Outline
Show full outline
Hide outline
Opinion | Open Access

Energy coupling mechanism of FO in a rotary ATP synthase: a model update

Xuejun C. Zhang1,2( ), Min Liu1
National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
College of Life Science, University of Chinese Academy of Sciences, Beijing 100049, China
Show Author Information

Graphical Abstract

Keywords

Energy Coupling MechanismProton WireUnidirectional RotationHalf ChannelProton Load

References

 
Benedek GB, Villars F (2000) Physics, with illustrative examples from medicine and biology (electricity and magmetism), 2nd edn. AIP Press, New York
Crossref
 

Boyer PD, (1988) Bioenergetic coupling to protonmotive force: should we be considering hydronium ion coordination and not group protonation?.Trends Biochem Sci 13:5-7
Crossref Google Scholar
 

Boyer PD, (1997) The ATP synthase–a splendid molecular machine.Annu Rev Biochem 66:717-749
Crossref Google Scholar
 

Dimroth P, von Ballmoos C, Meier T, Kaim G, (2003) Electrical power fuels rotary ATP synthase.Structure 11:1469-1473
Crossref Google Scholar
 

Gruber G, Manimekalai MS, Mayer F, Muller V, (2014) ATP synthases from archaea: the beauty of a molecular motor.Biochem Biophys Acta 1837:940-952
Crossref Google Scholar
 

Guo H, Bueler SA, Rubinstein JL, (2017) Atomic model for the dimeric FO region of mitochondrial ATP synthase.Science 358:936-940
Crossref Google Scholar
 

Hahn A, Vonck J, Mills DJ, Meier T, Kuhlbrandt W, (2018) Structure, mechanism, and regulation of the chloroplast ATP synthase.Science 360:eaat4318
Crossref Google Scholar
 

Junge W, Lill H, Engelbrecht S, (1997) ATP synthase: an electrochemical transducer with rotatory mechanics.Trends Biochem Sci 22:420-423
Crossref Google Scholar
 

Lightowlers RN, Howitt SM, Hatch L, Gibson F, Cox GB, (1987) The proton pore in the Escherichia coli F0F1-ATPase: a requirement for arginine at position 210 of the a-subunit.Biochem Biophys Acta 894:399-406
Crossref Google Scholar
 

Nakamoto RK, Baylis Scanlon JA, Al-Shawi MK, (2008) The rotary mechanism of the ATP synthase.Arch Biochem Biophys 476:43-50
Crossref Google Scholar
 

Silverstein TP, (2014) An exploration of how the thermodynamic efficiency of bioenergetic membrane systems varies with c-subunit stoichiometry of F(1)F(0) ATP synthases.J Bioenerg Biomembr 46:229-241
Crossref Google Scholar
 

Srivastava AP, Luo M, Zhou W, Symersky J, Bai D, Chambers MG, Faraldo-Gomez JD, Liao M, Mueller DM, (2018) High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane.Science 360:eaas9699
Crossref Google Scholar
 

Zhang XC, Liu M, Zhao Y, (2015) How does transmembrane electrochemical potential drive the rotation of Fo motor in an ATP synthase?.Protein Cell 6:784-791
Crossref Google Scholar
 

Zhang XC, Zhao Y, Heng J, Jiang D, (2015) Energy coupling mechanisms of MFS transporters.Protein Sci 24:1560-1579
Crossref Google Scholar
 

Zhang XC, Liu M, Lu G, Heng J, (2017) Thermodynamic secrets of multidrug resistance: a new take on transport mechanisms of secondary active antiporters.Protein Sci 27:595-613
Crossref Google Scholar
 

Zhang X, Yang H, Liu Z, Sun F, (2018) Thermodynamics of voltage-gated ion channels.Biophys Rep

Crossref Google Scholar
Biophysics Reports
Volume 5 Issue 2,
April 2019
Pages 61-64
DOI: 10.1007/s41048-018-0077-8
Cite this article:
Zhang XC, Liu M. Energy coupling mechanism of FO in a rotary ATP synthase: a model update. Biophysics Reports, 2019, 5(2): 61-64. https://doi.org/10.1007/s41048-018-0077-8

307

Views

10

Downloads

1

Crossref

0

Scopus

0

CSCD

Altmetrics
Received: 03 September 2018
Accepted: 15 September 2018
Published: 03 December 2018
© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Return