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Pooled analyses of randomized controlled trials on pyrotinib plus capecitabine and a rethink of the first‐line options for HER2‐positive relapsed or metastatic breast cancer

Show Author's information Xiuwen Guan1Fei Ma1,2 ( )Binghe Xu1,2( )
Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
Department of Medical Oncology and Clinical Trial Center, National Cancer Center/National Clinical Research Center for Cancer/ Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
Keywords: breast cancer, tyrosine kinase inhibitor, HER2‐targeted therapy

References(10)

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DOI
Swain SM, Miles D, Kim SB, Im YH, Im SA, Semiglazov V, et al. Pertuzumab, trastuzumab, and docetaxel for HER2‐positive metastatic breast cancer (CLEOPATRA): end‐of‐study results from a double‐blind, randomised, placebo‐controlled, phase 3 study. Lancet Oncol. 2020;21(4):519–30.
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Publication history

Received: 26 February 2022
Accepted: 06 June 2022
Published: 14 July 2022
Issue date: August 2022

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© 2022 The Authors.

Acknowledgements

We thank all the directors and study coordinators for presenting the referred clinical trials.

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This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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